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Cold-induced molecule from muscle helps worms live longer

Nature 21 October 2026 2 min read

In short

  • In nematodes, a metabolite induced by cold links low temperatures to a body-wide longevity signal.
  • The signal originates from muscle-derived molecules, according to the study summary.
  • The same signalling system has also been seen in human cells, the summary notes.

Why the Good News Desk likes this one

The finding connects a simple environmental cue, low temperature, to a signal that extends lifespan in an animal model. Because the same signalling system appears in human cells, it may point to a pathway worth studying further. The work is basic research, so it is far from any treatment for people.

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From Nature

Nature, Published online: 21 October 2026; doi:10.1038/d41586-026-03066-3 In nematodes, a metabolite induced by the cold links low temperatures to a body-wide signal that promotes longevity. This signalling system is also seen in human cells.

Read the full story at Nature Opens the publisher's site in a new tab.

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For kids

Worms are tiny animals that live in soil. Scientists found that when worms get cold, their muscles make a special molecule. This molecule sends a message around the body that helps them live longer. Do you think animals have other ways to protect themselves from the cold?

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