With large DNA fragment assembly, scientists can design microbes that produce countless complex products

A review in Quantitative Biology demonstrates that scientists can now reliably build and combine very large pieces of DNA, making it much easier to redesign microbes such as yeast and bacteria to act as efficient "cell factories." With these advances, whole biological pathways, and even extra chromosomes, can be assembled and inserted into cells, allowing microbes to produce complex products like medicines, fuels, and chemicals more efficiently than before.